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2022
Ahmed, Mona
Molecular determinants of radiosensitivity in Merkel cell carcinoma
Advisor: James DeCaprio
Atyeo, Caroline
Maternal:fetal functional antibody transfer for protection against SARS-CoV-2
Advisor: Galit Alter
Boudreau, Carolyn
The development of humoral breadth and protection against influenza
Advisor: Galit Alter
Clark, Sarah
Receptor binding and antibody neutralization of emerging RNA viruses
Advisor: Jonathan Abrham
Effectors of cell death in bacterial antiphage defense
Advisor: Philip Kranzusch
Frost, Tom
Molecular subtyping and vulnerability exploitation in Merkel cell carcinoma
Advisor: James DeCaprio
Gartin, Ashley
Dysregulation of developmental transcription factor programs in Merkel cell carcinoma
Advisor: James DeCaprio
Gauthier, Anna
Molecular and environmental aspects of innate immune pattern recognition
Advisor: Jonathan Kagan
Gebre, Makda
Design Optimization and Immune Kinetics of mRNA Vaccines
Advisor: Dan Barouch
Manny, Austin
Discovery and characterization of a novel dsRNA virus infecting the human parasite Trichomonas vaginalis
Advisor: Max Nibert
Miliotis, Christos
Non-coding genetic variants and microRNAs control gastric cancer immunogenicity
Advisor: Frank Slack
Moon-Walker, Alex
Functional assessment of the cell entry pathway of Lymphocytic choriomeningitis virus
Advisor: Sean Whelan
Nabel, Katherine
Molecular mechanisms for broad neutralization of emerging RNA viruses
Advisor: Jonathan Abrham
Nomburg, Jason
Using Sequencing Approaches to Characterize Tumor Microbial Communities and Viral Transcriptomes
Advisors: James DeCaprio and Matthew Meyerson
Phelps, Meredith
Broadly neutralizing antibody recognition of diverse HIV envelopes modulates effector function
Advisor: Alejandro Balazs
Tartell, Michael
Host Determinants of Viral Entry and Replication
Advisor: Sean Whelan
Welch, Nicole
Harnessing CRISPR-Cas systems for maximally active and multiplexed viral detection
Advisor: Pardis Sabeti
2021
Branigan, Timothy
Regulation of cell cycle transitions and CHK1 inhibitor sensitivity by MMB-FOXM1 feedback loops
Advisor: James DeCaprio
Ernandes, Mike
Oxidized Phospholipids as Antivirals and Immune Modulators
Advisor: Jonathan Kagan
Flagg, Meaghan
Mechanisms of disrupted intestinal epithelial homeostasis during HIV infection
Advisor: Doug Kwon
Govande, Apurva
Mechanisms of nucleotide signaling in bacterial and metazoan antiviral defense
Advisor: Philip Kranzusch
Herrmann, Toby
Molecular mechanisms of rhesus rotavirus entry
Advisor: Stephen Harrison
Karpel, Marshall
Vaccine responses in the context of impaired self-tolerance
Advisor: Shiv Pillai
Mertens, Max
The Relationship Between Herpes Simplex Virus 1 and the Cellular DNA Damage Response
Advisor: David Knipe
Pyle, Jesse
Functional regulation of an arenavirus polymerase complex
Advisor: Sean Whelan
Sangesland, Maya
Germline Encoded B Cell Receptor-Antigen Recognition
Advisor: Daniel Lingwood
Walsh, Michael
Engineering Replication Defective Herpes Simplex Virus 1 Vectors for the Treatment of Cancer
Advisor: David Knipe
2020
Cadena, Cristhian
Assembly of RIG-I signaling complexes in antiviral immunity
Advisor: Sun Hur
Chia, Bing Shao
Genome-wide Screen Identifies RTF2 as a Host Restriction Factor that Restricts Influenza A Virus Replication
Advisor: Nir Hacohen
Eaglesham, James
Evolution and Regulation of Antiviral Nucleotide Signaling
Advisor: Philip Kranzusch
Ferreira, Fernanda
New Insights into the Nature of the HIV-2 Reservoir
Advisor: Daniel Kuritzkes
Freije, Catherine
Sequence-informed, Cas13-based technologies for RNA viruses
Advisor: Pardis Sabeti
Joshi, Vinita
Delineating HIV-1 Evolutionary Pathways in an Individual with a Broadly Neutralizing Antibody Response
Advisor: Todd Allen
Lee, Phong
Assembly of Centromeric Nucleosomes in Budding Yeast
Advisor: Stephen Harrison
Lim, Matt
Evaluating measurement error in mass spectrometry-based proteomics
Advisor: Steven Gygi
Lin, Aaron
Characterizing Ebola virus mutation and selection between and within hosts
Advisor: Pardis Sabeti
Liu, Po-Ting
Establishment of the SIV Reservoir and Mechanisms of Viral Rebound in Rhesus Monkeys
Advisor: Dan Barouch
Tomezsko, Phillip
Next-generation sequencing techniques to study HIV-1 transcription and RNA structure
Advisor: Daniel Kuritzkes
2019
Barnett, Katherine
Phosphoinositide Regulation of Intracellular Nucleic Acid Sensors
Advisor: Jonathan Kagan
Cabral, Joseph
ATRX Mediated Restriction of Herpes Simplex Virus 1
Advisor: David Knipe
Dudek, Amanda
A Genome-Wide Knock-Out Screen Identifies Novel Host Cell Entry Factor Requirements for Divergent Adeno-Associated Virus Serotypes
Advisor: Luk Vandenberghe
Gootenberg, David
HIV-associated Gut Microbiome Differences and Immune Activation are Dependent on Host Context
Advisor: Doug Kwon
Iampietro, Mark
Immunogenicity and Cross-reactivity of Human and Rhesus Adenoviral Vectors
Advisor: Dan Barouch
Jennewein, Maddy
Harnessing the Fc Region: Antibody Fc Modulation in Infection and Pregnancy
Advisor: Galit Alter
Li, Bo
Genome-wide CRISPR screen Identifies Novel Host Dependency Factors for Influenza A Virus Infection
Advisor: Nir Hacohen
Park, Donglim
Merkel Cell Polyomavirus Oncogenes Generate Targetable Synthetic Lethality
Advisor: James DeCaprio
Schade, Amy
Mechanistic Insights into DREAM and RB Control of the Cell Cycle
Advisor: James DeCaprio
Sharaf, Radwa
Mechanisms of HIV-1 persistence and post-treatment control
Advisor: Daniel Kurtizkes
Tarnita, Roxana
Characterization of the FAM111A-mediated simian virus 40 host range phenotyp
Advisor: James DeCaprio
Wang, Liang Wei
Metabolic Remodeling of Human B-Cells During Latent Epstein-Barr Virus (EBV) Infection
Advisor: Benjamin Gewurz
Wang, May Kwang-Mei
Receptor-targeting small molecule inhibitors of Lassa and Ebola virus entry reveal a critical role for cholesterol in regulating receptor activity
Advisor: James Cunningham
Wang, Xiaoyi
DNA maintainer dependent epigenetic inheritance of gene silencing and histone H3K9 methylation
Advisor: Danesh Moazed
2018
Bentley, Peris
The Role of the SMC5/6 Complex in the Papillomavirus Replication Cycle
Advisor: Peter Howley
Blass, Eryn
Innate Immunity and Adenovirus Vector Immunization
Advisor: Dan Barouch
Chiang, Jessica
Activation and Antagonism of RIG-I-Mediated Innate Immune Signaling by Herpes Simplex Virus 1
Advisor: Michaela Gack
Franz, Kate
STING engages distinct antiviral mechanisms to restrict RNA virus and DNA virus replication
Advisor: Jonathan Kagan
Kang, Zi Han
Antibody responses against HIV-1 vaccine candidates
Advisor: Dan Barouch
Lawler, Jessica
Functional analysis of multiple activities associated with the herpes simplex virus-1 DNA polymerase
Advisor: Donald Coen
Neidermyer, William
A Global View of Translation in Vesicular Stomatitis Virus Infected Cells
Advisor: Sean Whelan
Peters, Cole
Restriction of γ34.5-deleted Oncolytic Herpes Simplex Virus-1 in Glioblastoma Stem Cells and Therapies to Treat Them
Advisor: Samuel Rabkin
Timpona, Joseph
VSV vectors as vaccines for emerging viruses and as probes for entry pathways
Advisor: Sean Whelan
Wellman, Tyshia
Epigenetic Alterations Induced by Human Papillomavirus E6 and E7 Oncoproteins
Advisor: Karl Münger
2017
Ayeni, Christian
Innate Immune Responses to Replication-Competent and -Deficient HSV-2
Advisor: David Knipe
Dev, Jyoti
Structural and functional characterization of viral membrane proteins by solution NMR spectroscopy
Advisor: James Chou
Harden, Mallory
Dysregulation of Host Cellular microRNA Expression by the Human Papillomavirus E6 and E7 Oncoproteins
Advisor: Karl Münger
Jiang, Sizun
Epstein Barr Virus Drives Cancer through Transcriptional Regulation and Chromatin Dynamics
Advisor: Elliott Kieff
Meyers, Jordan
Cutaneous papillomavirus E6 inhibit NOTCH and TGF-beta signaling to disrupt keratinocyte differentiation
Advisor: Karl Münger
Robinson, Lindsey
Reconstructing the Cell Entry Pathway of an Extinct Virus
Advisor: Sean Whelan
Wilkie, Adrian
The processes mediating capsid trafficking during human cytomegalovirus nuclear egress
Advisor: Donald Coen
2016
Berrios, Christian
Simian Virus 40 and Human Polyomavirus Oncogenic Perturbations
Advisor: James DeCaprio
Bricault, Christine
Multivalent Vaccination Strategies with Novel HIV-1 Trimeric Envelope Proteins Elicit Improved Neutralizing Antibody Responses Compared to Monovalent Vaccination Regimens
Advisor: Dan Barouch
Durbin, Ann
Nucleotide modifications of RNA suppress RIG-I antiviral signaling by unique mechanisms
Advisor: Lee Gehrke
Hill, Alison
Emergence of simian immunodeficiency virus in rhesus macaques is characterized by changes in structural and accessory genes that enhance fitness in the new host species
Advisor: Welkin Johnson
Ita, Sergio
Adaptive Evolution of the SIV Envelope Protein during Early SIV Infection
Advisor: Welkin Johnson
Provine, Nicholas Mcdermott
CD4 T Cells Regulate Adenovirus Vector-Elicited Cellular and Humoral Immune Responses
Advisor: Dan Barouch
Rahmberg, Andrew
Gene Expression and CD4+ T Cell Susceptibility to SIV
Advisor: Paul Johnson
2015
Conwell, Sara
TRIM27 in HSV-1 Infection: A Story of Loss and Death
Advisor: David Knipe
Davis, Meredith
Evasion of MDA5-mediated Innate Immunity by Paramyxoviruses
Advisor: Michaela Gack
Herrman, Marissa Ann
Neutralizing Antibodies to Epstein Barr Virus in the Rhesus Macaque Animal Model and in Humans
Advisor: Frederick Wang
Jurado, Kellie Ann
Allosteric integrase inhibitors reveal a role for integrase during HIV-1 maturation
Advisor: Alan Engelman
Lee, Jennifer
Epigenetic Regulation of Lytic and Latent Herpes Simplex Virus 1 Infection
Advisor: David Knipe
Leigh, Kendra
Structural Studies of a Subunit of the Murine Cytomegalovirus Nuclear Egress Complex
Advisor: James Hogle
Piccinotti, Silvia
Rabies Glycoprotein-Mediated Uptake into Epithelial Cells and Compartmentalized Primary Neuronal Culture
Advisor: Sean Whelan
Soghoian, Damien
HIV-specific CD4 T cells and Viral Control
Advisor: Bruce Walker
Soh, Timothy
Single particle studies of vesicular stomatitis virus assembly
Advisor: Sean Whelan
Sun, Eileen
Investigating host protein function and developing assays for influenza virus infection
Advisor: Xiaowei Zhuang
Thorpe, Lauren
PI3K regulatory subunit p85alpha plays a tumor suppressive role in the transformation of mammary epithelial cells
Advisor: Jean Zhao
Yoon, Rosa
Merkel Cell Polyomavirus Small T Antigen Perturbs the Cellular DNA Damage Response
Advisor: James DeCaprio
2014
Ellis, Laura
Investigating the roles of the JC virus agnogene and regulatory region using a naturally occurring, pathogenic viral isolate
Advisor: Igor Koralnik
Gardner, Matthew
TARGETING THE CD4- AND CORECEPTOR-BINDING SITES OF THE HIV-1 ENVELOPE GLYCOPROTEIN
Advisor: Michael Farzan
Guth, Charles
Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus (HIV-1) Capsid
Advisor: Joseph Sodroski
Mahan, Alison
Regulation and Programming of Antibody Effector Function through IgG Glycosylation
Advisor: Galit Alter
Matreyek, Kenneth
HIV-1 capsid engages nucleoporin NUP153 to promote viral nuclear entry
Advisor: Alan Engelman
McCarthy, Kevin
Viral and Host Determinants of Primate Lentivirus Restriction by Old World Primate TRIM5alpha Proteins
Advisor: Welkin Johnson
Oztop, Ilker
THE FUNCTIONAL INTERPLAY BETWEEN TNPO3, CPSF6 AND HIV-1 CA
Advisor: Alan Engelman
Quinlan, Brian
Directed Evolution of Peptide Inhibitors of HIV-1 Entry
Advisor: Michael Farzan
Schafer, Jamie
Rhesus macaque KIR recognition of MHC class I molecules: Ligand identification and modulation of interaction by SIV peptides
Advisor: David Evans
Teigler, Jeffrey
Differential Innate Immune Stimulation Elicited by Adenovirus and Poxvirus Vaccine Vectors
Advisor: Dan Barouch
Tong, Haoxuan
PI3K Isoform Dependence and Translational Regulation of c-MYC in PTEN-Deficient Leukemia
Advisor: Thomas Roberts
2013
Bollman, Brooke
Role of the Capsid Helix 4-5 Loop in Equine Infectious Anemia Virus Infection
Advisor: Joseph Sodroski
Clark, Margaret
Exploring Dengue Virus Entry Through Small Molecule Inhibition and Mutagenesis of the Envelope Protein
Advisor: Priscilla Yang
Lim, Hui Jun
Dynamic regulation of histone lysine methylation via the ubiquitin-proteasome system.
Advisor: Yang Shi
Orzalli, Megan
Inhibition of Nuclear DNA Sensing by Herpes Simplex Virus 1
Advisor: David Knipe
Tan, Meng Kwang Marcus
Deciphering the biological functions of F-box proteins through the use of Parallel Adaptor Capture (PAC) proteomics.
Advisor: J.Wade Harper
Tan, Min Jie Alvin
Identification of the Cellular Proteins and Pathways Engaged by the Bovine Papillomavirus Type 1 E6 and E7 Proteins
Advisor: Peter Howley
Yen, Po-Jen
SIV envelope glycoprotein determinants of macrophage tropism and their relationship to neutralization sensitivity and CD4-independent cell-to-cell transmission
Advisor: Dana Gabuzda
2012
Alpert, Michael
Antibodies in Vaccine Protection against SIV and HIV-1 Infection
Advisor: David Evans
Bruchez, Anna
Niemann-Pick C1 is essential for Ebola virus infection and a target of small molecule inhibitors
Advisor: James Cunningham
DeGrace, Marciela
RNAi screens in primary human lung cells reveal Hermansky-Pudlak Syndrome proteins as influenza suppressors
Advisor: Nir Hacohen
Kim, Irene
Mechanisms of membrane disruption by viral entry proteins
Advisor: Stephen Harrison
Kranzusch, Philip
Architecture and regulation of the arenavirus polymerase complex
Advisor: Sean Whelan
Lee, Amy
Ribosome-mediated specificity in vesicular stomatitis virus mRNA translation defines a new role for rpL40 during initiation
Advisor: Sean Whelan
Mefford, Megan
MOLECULAR AND BIOINFORMATIC ANALYSIS OF NEUROTROPIC HIV ENVELOPE GLYCOPROTEINS
Advisor: Dana Gabuzda
Mukerji, Joya
A NOVEL EXOCYST-BASED MECHANISM FOR HIV NEF-MEDIATED ENHANCEMENT OF INTERCELLULAR NANOTUBE FORMATION
Advisor: Dana Gabuzda
Rahman, Shaila
Molecular insight into function of the evolutionarily conserved Brd4 extraterminal domain (ET) and mechanism of Brd4 functions in human diseases
Advisor: Peter Howley
Spangle, Jennifer
Regulation of Growth Factor and Nutrient Sensing Pathways by Human Papillomavirus E6 Proteins
Advisor: Karl Münger
2011
De Leon-Vazquez, Erika
Investigation of the Roles of the KSHV Latency Associated Nuclear Antigen Internal Regions in Episome Persistence.
Advisor: Kenneth Kaye
Morelli, Marco
The Role of HIV-1 Membrane in Neutralization by gp41 MPER-directed Broadly Neutralizing Antibodies
Advisor: Stephen Harrison
Schmidt, Aaron
Inhibition by Small Molecules and Peptides of Dengue-virus Fusion and Entry
Advisor: Stephen Harrison
2010
Aoki, Scott
The Role of Outer Capsid Glycoprotein VP7 in Assembly, Neutralization, and Maturation of the Rotavirus Triple Layered Particle
Advisor: Stephen Harrison
Rogers, Thomas
Intrinsic Immune Response to Viral Replication in Primates
Advisor: Norman Letvin
Uzri, Dina
RIG-I-Dependent Innate Immune Signaling by Hepatitis C Virus RNAS
Advisor: Lee Gehrke
2009
Erlandson, Karl
Interactions of the SecY Channel and the SecA ATPase with a Translocating Polypeptide
Advisor: Tom Rapoport
Johnson, Karen
THE INHIBITION OF TYPE I INTERFERON SIGNALING BY HERPES SIMPLEX VIRUS 1
Advisor: David Knipe
Laird, Melissa
HIV/SIV VARIABLE LOOPS AS TARGETS AND ELICITORS OF ANTIBODIES THAT NEUTRALIZE VIRAL INFECTIVITY
Advisor: Ronald Desrosiers
Maliszewski, Laura
The Role of miRNAs in HIV Infection of Primary Macrophages
Advisor: Judy Lieberman
Rud, Debrah
Identification of FAM111A as a Novel Simian Virus 40 Large T Antigen Binding Protein that Affects Viral Host Range
Advisor: James DeCaprio
Silva, Laurie
The Roles of Phosphorylation and the Carboxy-terminus in the Function of the Human Cytomegalovirus Processivity Factor, UL44
Advisor: Donald Coen
2008
Boutwell, Christian
INVESTIGATION OF THE ADAPTATION OF HIV-1C TO THE HOST CTL IMMUNE RESPONSE
Advisor: Myron Essex
Bowman, John
Characterization of Expression of the Herpes Simplex Virus Type-1 ICP22 and Us1.5 Proteins
Advisor: Priscilla Schaffer
Cureton, David
VIRAL AND CELLULAR DETERMINANTS OF VESICULAR STOMATITIS VIRUS ENTRY
Advisor: Sean Whelan
Fontaine Rider, Errin
HERPES SIMPLEX VIRUS IMMEDIATE EARLY PROTEINS AND EFFECTS ON TRANSLATION
Advisor: David Knipe
Garcia, Maria
The molecular basis of Herpesvirus Saimiri oncogenicity
Advisor: Jae Jung
Huang, I-Chueh
ENZYMATIC REGULATION OF VIRAL ENTRY
Advisor: Michael Farzan
Ivanovic, Tijana
From Virion to Viral Factory: Reovirus Particle Transformations Leading to Cell Entry and Productive Infection
Advisor: Max Nibert
Kushnir, Anna
THE EFFECT OF CELLULAR STRESS-INDUCED FACTORS ON HSV-1 GENE EXPRESSION AND REPLICATION
Advisor: Priscilla Schaffer
Manuel, Edwin
Immunodominance in Primate Immunodeficiency Virus Infection
Advisor: Norman Letvin
Mirchandani, Kanchan
A role for the Fanconi Anemia pathway in error-prone DNA damage tolerance
Advisor: Alan D'Andrea
Nguyen, Christine
CENTROSOMAL AND MITOTIC ABERRATIONS: MECHANISTIC INSIGHTS INTO HPV16 E7 ONCOPROTEIN-INDUCED GENOMIC DESTABILIZATION
Advisor: Karl Münger
Radoshitzky, Sheli
CELL ENTRY OF NEW WORLD HEMORRHAGIC FEVER ARENAVIRUSES
Advisor: Michael Farzan
Trask, Shane
The mechanism of membrane penetration by rotavirus
Advisor: Stephen Harrison
Wass, Amanda
BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE VPg URIDYLYLATION COMPLEX OF POLIOVIRUS
Advisor: James Hogle
Wu, Su
YY1 functions in homologous recombination DNA repair and mice spermatogenesis
Advisor: Yang Shi
2007
Arnold, Michelle
Roles of muNS in Reovirus Factory Formation
Advisor: Max Nibert
Bryant, Kevin
REGULATION OF TRANSLATION DURING HERPES SIMPLEX VIRUS-1 INFECTION
Advisor: Donald Coen
Chen, Adrienne
Epstein-Barr Virus Nuclear Antigen 3B- and 3C-regulated cellular genes in virus-immortalized B cells
Advisor: Frederick Wang
Dunfee, Rebecca
ENVELOPE-RECEPTOR INTERACTIONS OF NEUROTROPIC HIV
Advisor: Dana Gabuzda
He, Xi
Regulation of SNF2h Chromatin Remodeling Activity
Advisor: Robert Kingston
Kattenhorn, Lisa
Identification and Characterization of a Novel Deubiquitinating Activity Conserved Within the Herpesvirus Large Tegument Proteins
Advisor: Hidde Ploegh
Link, Malen
MECHANISM OF EXPRESSION AND FUNCTIONAL ANALYSIS OF HERPES SIMPLEX VIRUS TYPE-1 PROTEINS OBPC-1 AND OBPC-2
Advisor: Priscilla Schaffer
Perron, Michel
TRIM5ahu: An Innate Cellular Defense Against N-tropic Murine Leukemia Virus Infection in Humans
Advisor: Joseph Sodroski
Redd, Andrew
Human Immunodeficiency Virus Type 1 Subtype C and Hematopoiesis
Advisor: Myron Essex
Yoder, Joshua
Molecular Rearrangements of Recombinant and Authentic Rotavirus VP5*
Advisor: Phil Dormitzer
2006
Agopian, Kristin
Characterization of Primary HIV-1 NEF Alleles and Their Association with P21-Activated Kinase 2
Advisor: Dana Gabuzda
Gomila, Raúl
Identification and Characterization of Host Factors that Bind the Conserved 3' Terminal Stem Loop RNA of Flaviviruses
Advisor: Lee Gehrke
Greenland, John
Vaccine antigen expression and immune responses
Advisor: Norman Letvin
Hughes, Christina
Menin is a Component of SET1-Like Histone Methyltransferase Complexes that Regulate Gene Expression
Advisor: Matthew Meyerson
Kelley-Clarke, Brenna
Characterization and functional assessment of the Kaposi's sarcoma herpesvirus latency-associated nuclear antigen C-terminal chromosome binding domain
Advisor: Kenneth Kaye
Melroe, Gregory
Herpes Simplex Virus Inhibition of Innate Type-I Interferon Induction
Advisor: David Knipe
Myers, Kimberly
Membrane Perforation and Related Structural Transitions by Reovirus Particles
Advisor: Max Nibert
Skaar, Jeffrey
Biochemical and Genetic Characterization of Cullin 7- and PARC-containing Complexes
Advisor: James DeCaprio
2005
Barbera, Andrew
Role of the Latency Associated Nuclear Antigen N-terminus in Chromosome Association and Kaposi's Sarcoma-Associated Herpesvirus DNA Persistence
Advisor: Kenneth Kaye
Chan, Amanda
The Role of Intramolecular Interactions in HHR23A Function in Ubiquitin-Mediated Protein Degradation
Advisor: Peter Howley
Jackson, Shawn
Vaccine-Elicited Memory Cytotoxic T Lymphocytes
Advisor: Norman Letvin
Kasper, Jocelyn
SV40 Large T Antigen Inactivates CUL7, a p53-Interacting Cullin
Advisor: James DeCaprio
Lu, Richard
Genetic Analyses of Human Immunodeficency Virus Type 1 Integrase Mutants
Advisor: Alan Engelman
Petrillo, Jessica
Characterization of RNA and Protein Determinants of Alfalfa Mosaic Virus Replication
Advisor: Lee Gehrke
Poulin- Porter, Danielle
The Carboxyl-Terminal Domain of Large T Antigen is Essential for the Simian Virus 40 Life Cycle
Advisor: James DeCaprio
Suscovich, Todd
Modulation of Tapasin Expression in Primary Effusion Lymphoma
Advisor: David Scadden
Thomas, Seddon
The Role of Chemokine Receptors in CD1D-Restricted NK T Cell Trafficking
Advisor: Andrew Luster
Wong, Sharyl
Prediction and Characterization of Genetic Interactions
Advisor: Frederick Roth
2004
Appleton, Brent
The Three-Dimensional Structure and Functional Studies of the Human Cytomegalovirus DNA Polymerase Subunit, UL44
Advisor: James Hogle
Hershberger, Karen
Diverse Killer-cell Ig-like Receptors (KIRs) of Rhesus and Sabaeus Monkeys: Evidence for Recombination Events in the Evolution of KIRs
Advisor: Norman Letvin
Holm, Geoffrey
Mechanisms of Bystander T Cell Apoptosis in HIV-1 Infection
Advisor: Dana Gabuzda
Lorenzo, Mayra
Downregulation of MHC Class I Molecules by Herpesviruses: Usurpation of Intracellular Trafficking Pathways
Advisor: Hidde Ploegh
Mehle, Andrew
HIV-1 VIF: A Novel SOCS-Box Protein that Targets APOBEC3G for Proteasomal Degradation
Advisor: Dana Gabuzda
Peyerl, Friedrich
Structural Constraints on Primate Immunodeficiencey Virus Escape from Cytotoxic T Lymphocytes
Advisor: Norman Letvin
Smith, Jason
Thiol-dependent Activation of Alpharetrovirus Infection
Advisor: James Cunningham
2003
Day, Cheryl
CD4+ T-Helper Cell Responses in Hepatitis C Virus Infection
Advisor: Bruce Walker
Klucking, Sara
Cytopathic Avian Retroviruses and the Death Receptor TVB
Advisor: John Young
LaBonte, Jason
HIV-1 Single Round Vector Systems for the Expression of Envelope Glycoproteins in Primary Cells
Advisor: Joseph Sodroski
Lin, Jeffrey
Epstein-Barr Virus Nuclear Antigen 3C (EBNA3C) Regulates Transcription through Viral and Cellular Factors
Advisor: Elliott Kieff
Luftig, Micah
Characterization of Epstein-Barr Virus Latent Membrane Protein 1 Mediated NFkB Activation
Advisor: Elliott Kieff
Randell, John
Processivity of the Herpes Simplex Virus DNA Polymerase: Role of High-Affinity DNA Binding by the Processivity Subunit
Advisor: Donald Coen
Wensel, David
A Virus-Virus Interaction Circumvents the Virus Receptor Requirement for Infection by Pathogenic Retroviruses
Advisor: James Cunningham
2002
Cooper, Andrew
Epstein-Barr Virus Nuclear Antigen 3A (EBNA-3A) Can Inhibit c-myc Expression and Lymphoblastoid Cell Growth
Advisor: Elliott Kieff
LaBonte, Michelle
Characterization of the CD94/NKG2 Family of Molecules in the Rhesus Monkey
Advisor: Norman Letvin
McNamee, Elizabeth
Regulation of HSV Gene Expression: Two Viral Functions Implicated in the Stimulation of Late Gene Transcription
Advisor: David Knipe
Taylor, Travis
Intranuclear Localization of the Herpes Simplex Virus ICP8 Protein
Advisor: David Knipe
2001
Brockman, Mark
Mechanisms of the Humoral Immune Response to Herpes Simplex Virus Infection
Advisor: David Knipe
Furman, Craig
DEF-1: An ARF Gap that Localizes to Focal Adhesions and Regulates Cell Attachment and Motility
Advisor: Thomas Roberts
Kleijnen, Mauritius
Ubiquitin-like hPLIC Proteins: A Link between Ubiquitination and Proteasomal Degradation
Advisor: Peter Howley
Kolchinsky, Peter
CD4-Independence of a CCR5-Using HIV-1 Primary Isolate
Advisor: Joseph Sodroski
Mittler, Ellis Stewart
Mechanisms and Pathways of Picornaviral Entry into HeLa Cells
Advisor: James Hogle
2000
Adkins- Huet, Heather
Indentification and Characterization of TNFR-like Receptors for Subgroups B, D and E Avian Leukosis Viruses: Two Isoforms of a Common Receptor Explain Non-reciprocal Receptor Interference between Cytopathic and Non-cytopathic Avian Retroviruses
Advisor: John Young
Csejtey Olland, Andrea
Structure of the Reovirus Outer Capsid Protein Sigma 3
Advisor: Stephen Harrison
DeTulleo, Louis
Viral Usage of the Clathrin Endocytic Pathway
Advisor: Tomas Kirchhausen
Jun, Helen (Toni)
Analysis of Cellular Signaling Pathways Activated by Polyomavirus Middle T Antigen
Advisor: Thomas Roberts
Snitkovsky, Sophie
Targeting of Retroviral Vectors to Specific Cell Types Mediated by Soluble Retroviral Receptor-Ligand Bridge Proteins
Advisor: John Young
1999
Means, Robert
Factors Affecting the Antigenicity and Immunogenicity of SIVmac Envelope
Advisor: Ronald Desrosier
Powell, Christina M. H.
Role of the Mammalian Transcription Factor LSF at the G1/S Transition of the Cell Cycle
Advisor: Ulla Hansen
Rizzuto, Carlo
Molecular Interactions in HIV-1 Entry
Advisor: Joseph Sodroski
1998
Lu, Wange
Pak1 Kinase: A Nck Adaptor Interacting Protein
Advisor: Bruce Mayer
Puder, Mark
Intracellular Movement and Binding of Leukotriene C4 and Glutathione Conjugates
Advisor:
1997
Borras-Rodriquez, Ana María
Analysis of the Promoter Elements in the Epstein-Barr Virus Lytic Switch Gene, BZLF1
Advisor: Jack Strominger
Chow, Connie Shui-Yi
Structure/Function Analysis of the Herpes Simplex Virus DNA Polymerase Subunit UL42: A Novel Processivity Factor
Advisor: Donald Coen
Peng, Cheng-Yuan
Regulation of Human Cdc25C Phosphatase
Advisor: Helen Piwnica-Worms
Stubdal, Hilde
Novel Mechanism for Inactivation of the pRB-related Proteins p130 and p107 Mediated by the J-domain of SV40 large T Antigen
Advisor: James DeCaprio
Uprichard, Susan L.
Expression and Assembly of the HSV DNA Replication Proteins
Advisor: David Knipe
1996
Puglielli, Maryann Theresa
Regulation of EBNA Gene Promoters in Epstein-Barr Virus Immortalized B Cells
Advisor:
1995
Bachelder, Robin
Characterization of the CD4-Specific Antibody Response of a Recombinant Soluble CD4-Immunized, HIV-1-Infected Human through the Construction of a Combinatorial Fab Library
Advisor: Norman Letvin
Baradaran, Khandan
Identification and Characterization of a Novel HSV-1 Origin Binding Protein
Advisor: Priscilla Schaffer
Curtin, Kathryn
Regulated Nuclear Entry of the period Protein Contributes to a Circadian Clock in Drosophila
Advisor:
Freeman, Robert
Molecular Cloning and Characterization of the SH2 Domain-containing Protein Tyrosine Phosphatase SH-PTP2
Advisor: Benjamin Neel
Hooper, Jay
Analysis of the Mechanism of Reovirus Entry into Cells
Advisor: Bernie Fields
Kramer, Martha
Quantification of Herpes Simplex Virus DNA and Transcripts during Latent Infection in Mouse Trigeminal Ganglia by Reverse Transcriptase PCR
Advisor: Donald Coen
Lee, Jeng-Shin
Transcriptional Regulation by Yin-Yang 1 and Adenovirus E1A
Advisor: Yang Shi
Li, John
Construction and Characterization of Recombinant Simian/Human Immunodeficiency Virus (SHIV) Expressing the HIV-1 Envelope Glycoproteins
Advisor: Joseph Sodroski
Renjifo, Boris
Human T-cell Leukemia Virus Type I (HTLV-I): Pathogenesis of Tropical Spastic Paraparesis/HTLV-I-associated Myelopathy (TSP/HAM)
Advisor: Myron Essex
1994
Agarwal, Sadhana
Regulation of Post-Translational Modifications of c-fos and c-jun
Advisor: Thomas Roberts
Edmonson, Paul
Development of a Simian Immunodeficiency Virus (SIV) Pathogen
Advisor:
Shirodkar, Suman
Functional Interactions of the Transcription Factor E2F with Cellular Proteins
Advisor: David Livingston
1993
Bartel, David
RNA Recognition and Catalysis: I. The HIV Rev-RRE Interaction II. New Ribozymes from Random Sequences
Advisor: Jack Szostak
Casaz, Paul
Regulation of Transcription by Simian Virus 40 Large Tumor Antigen
Advisor: Ulla Hansen
Morin, Merribeth
Pathogenesis of Reovirus Infection in the Lungs
Advisor: Bernie Fields
Prentice, Holly
Characteriztion of Heat Shock Factor and Mammalian Promoter Elements in the Fission Yeast Schizosaccharomyces pombe
Advisor: Robert Kingston
Xia, Kai
Phosphorylation of the HSV-1 Major Regulatory Protein ICP4
Advisor: David Knipe
1992
Burns (Wooley), Dawn
Envelope Sequence Variation and Immune Selection of Simian Immunodeficiency Virus (SIV) in Persistently Infected Rhesus Monkeys
Advisor: Ronald Desrosiers
Farnet, Chris
The Integration and Circularization of Human Immunodeficiency Virus Type 1 DNA in vitro
Advisor:
Jacobson, Jennie
Individual and Combinatorial Effects of Non-Lethal Mutations on HSV-1 Pathogenesis and Reactivatable Latent Infection in a Mouse Model
Advisor: Donald Coen
Mundschau Kasman, Laura
Identification of Platelet-Derived Growth Factor Signal Transduction Second Messenger Pathways
Advisor: Douglas Faller
1991
Batson, Susan
In Vitro Transcriptional Analysis of in Vivo Assembled Chromatin
Advisor: Ulla Hansen
Kristal, Bruce
Multiple Roles of the Feline Leukemia Virus Envelope Glycoprotein
Advisor:
Mullen, Mary
Alternative Pre-mRNA Splicing of a-Tropomyosin
Advisor:
Shepard, Alyssa
Genetic Analysis of the Herpes Simplex Virus Type 1 Regulatory Protein ICP4
Advisor: Neal DeLuca
Young, Alexander
Polyoma Virus Middle T Effects on Elements of Signal Transduction
Advisor: Thomas Benjamin
1988
Smith, Colton
Molecular Genetics of the Herpes Simplex Virus Type 2 Gene Encoding ICP4
Advisor: Priscilla Schaffer