# Faculty [### Arlene Sharpe ](/people/arlene-sharpe) [arlene\_sharpe@hms.harvard.edu](mailto:arlene_sharpe@hms.harvard.edu)Chair & Kolokotrones University Professor The major interest of the Sharpe laboratory is to study functions of T cell costimulatory pathways and their immunoregulatory roles in controlling the balance between T cell activation and tolerance. Costimulation is of therapeutic interest because... ![Photo of Arlene Sharpe](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Sharpe_Arlene.jpg?itok=spXbTWaO) [### Jonathan Abraham ](/people/jonathan-abraham) Associate Professor of Microbiology We use methods in molecular biology, immunology, and structural biology to study host-pathogen interactions, with the goal of informing strategies aimed at treating or preventing infection. Several enveloped RNA viruses cause human viral hemorrhagic... ![Jonathan Abraham](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Abraham_Jonathan.jpg?itok=I3XdwPSa) [### Alejandro Benjamin Balazs ](/people/alejandro-benjamin-balazs) Assistant Professor of Medicine My laboratory employs approaches rooted in synthetic immunology as a means of engineering or enhancing the natural immune system with the goal of understanding, preventing and treating HIV infection. We are currently applying these approaches to a number... ![Alejandro Balazs](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Balazs_Alejandro.jpg?itok=4SDpy1O4) [### Dan Hung Barouch ](/people/dan-hung-barouch) William Bosworth Castle Professor of Medicine Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine... ![Man in a blue suit jacket and tie smiles at the camera](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2025-08/Barouch%20Photo%2010-15-24.jpg?itok=Wkz3YU2h) [### Constance L. Cepko ](/people/constance-l-cepko) Bullard Professor of Genetics and Neuroscience We are interested in the mechanisms that direct development and degeneration of the central nervous system (CNS) of vertebrates. We are focusing our studies on the vertebrate retina, a relatively simple and well-characterized area of the CNS. We have used... ![Constance Cepko](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Cepko_Constance.jpg?itok=zSH90e6f) [### Bing Chen ](/people/bing-chen) Rosalind Franklin, PhD Professor of Pediatrics Our research centers on elucidating molecular mechanisms of HIV (human immunodeficiency virus) viral entry -- that is, how HIV enters host cells and how the viral envelope protein interacts with host cellular receptors. Insights gained from these studies... ![Bing Chen](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Chen_Bing.jpg?itok=Tr3i85xP) [### Raymond Taeyong Chung ](/people/raymond-taeyong-chung) Professor of Medicine Our laboratory has been focused on the mechanisms of HCV persistence and pathogenesis. Hepatitis C virus infects 170 million persons worldwide and is remarkable for its predilection for chronicity. It is also a leading cause of chronic liver disease... ![Raymond Chung](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Chung_Raymond.jpg?itok=Fz_vNBGA) [### George Mcdonald Church ](/people/george-mcdonald-church) Robert Winthrop Professor of Genetics Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in particular, personal genomics and biofuels. We have developed next-generation sequencing methods to analyze the... ![George Church](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/george-church-headshot-004-square.jpg?itok=j8yz8Gs7) [### Kizzmekia Corbett ](/people/kizzmekia-corbett) [kizzmekia\_corbett@hsph.harvard.edu](mailto:kizzmekia_corbett@hsph.harvard.edu)Assistant Professor of Immunology and Infectious Diseases Dr. Corbett uses her viral immunology expertise to propel novel vaccine development for pandemic preparedness, including mRNA-1273, a leading vaccine against SARS-CoV-2. The vaccine concept incorporated in mRNA-1273 was designed by Dr. Corbett's NIH team... ![Kizzmekia Corbett](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Corbett_Kizzmekia.jpg?itok=mJOPaJhV) [### James Morgan Cunningham ](/people/james-morgan-cunningham) Associate Professor of Medicine (Microbiology and Molecular Genetics) My laboratory is interested in the pathogenesis of virus-induced leukemia. In particular, we study the mechanism of infection by retroviruses that cause leukemia in mice. As part of these studies, we have identified the receptors that these viruses use to... ![James Cunningham](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/Cunningham_James_0.jpg?itok=0ZkyU2Ez) [### Alan David D'Andrea ](/people/alan-david-dandrea) [alan\_dandrea@dfci.harvard.edu](mailto:alan_dandrea@dfci.harvard.edu)Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by germline or somatic mutation, leads to genomic instability, cellular sensitivity to ionizing radiation... ![Alan D'Andrea](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/D%27Andrea_Alan.jpg?itok=8cP6YEFW) [### Victoria D'Souza ](/people/victoria-dsouza) Professor of Molecular and Cellular Biology Retroviruses are associated with a wide range of clinical diseases, including leukemia, tumors, and acquired immunodeficiency syndrome. Human immunodeficiency virus (HIV) is an exceptionally deadly retrovirus that has caused more than 20 million deaths... ![Victoria D'Souza](/sites/g/files/omnuum5516/files/styles/hwp_4_5__690x865/public/2024-09/D%27Souza_Victoria.png?itok=tZq60dTp) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [4](?page=3 "Go to page 4") - [5](?page=4 "Go to page 5") - [ Next page chevron\_right ](?page=1 "Go to next page")