#  Alumni 

 



 ##  

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## Add or update your contact information 

Stay in touch with us by updating your information and sharing your current position using [this form](https://hms.az1.qualtrics.com/jfe/form/SV_1B2SAkNZbdLOfQh).

[2022](/about/alumni#2022)| [2021 ](/about/alumni#2021)| [2020](/about/alumni#2020) | [2019](/about/alumni#2019) | [2018](/about/alumni#2018) | [2017](/about/alumni#2017) | [2016](/about/alumni#2016) | [2015](/about/alumni#2015) | [2014](/about/alumni#2014) | [2013](/about/alumni#2013) | [2012](/about/alumni#2012) | [2011](/about/alumni#2011) | [2010](/about/alumni#2010)

[2009](/about/alumni#2009) | [2008](/about/alumni#2008) | [2007](/about/alumni#2007) | [2006](/about/alumni#2006) | [2005](/about/alumni#2005) | [2004](/about/alumni#2004) | [2003](/about/alumni#2003) | [2002](/about/alumni#2002) | [2001](/about/alumni#2001) | [2000](/about/alumni#2000)

[1999](/about/alumni#1999) | [1998](/about/alumni#1998) | [1997](/about/alumni#1997) | [1996](/about/alumni#1996) | [1995](/about/alumni#1995) | [1994](/about/alumni#1994) | [1993](/about/alumni#1993) | [1992](/about/alumni#1992) | [1991](/about/alumni#1991) | [1988](/about/alumni#1988)



 

##  2022 

**Ahmed, Mona**  
*Molecular determinants of radiosensitivity in Merkel cell carcinoma*  
Advisor: James DeCaprio

**Atyeo, Caroline**  
*Maternal:fetal functional antibody transfer for protection against SARS-CoV-2*  
Advisor: Galit Alter

**Boudreau, Carolyn**  
*The development of humoral breadth and protection against influenza*   
Advisor: Galit Alter

**Clark, Sarah**  
Receptor binding and antibody neutralization of emerging RNA viruses  
Advisor: Jonathan Abrham

**Duncan-Lowey, Brianna**

*Effectors of cell death in bacterial antiphage defense*  
Advisor: Philip Kranzusch

**Frost, Tom**  
*Molecular subtyping and vulnerability exploitation in Merkel cell carcinoma*  
Advisor: James DeCaprio

**Gartin, Ashley**  
*Dysregulation of developmental transcription factor programs in Merkel cell carcinoma*  
Advisor: James DeCaprio

**Gauthier, Anna**  
*Molecular and environmental aspects of innate immune pattern recognition*  
Advisor: Jonathan Kagan

**Gebre, Makda**  
*Design Optimization and Immune Kinetics of mRNA Vaccines*  
Advisor: Dan Barouch

**Manny, Austin**  
*Discovery and characterization of a novel dsRNA virus infecting the human parasite Trichomonas vaginalis*  
Advisor: Max Nibert

**Miliotis, Christos**  
*Non-coding genetic variants and microRNAs control gastric cancer immunogenicity*  
Advisor: Frank Slack

**Moon-Walker, Alex**  
*Functional assessment of the cell entry pathway of Lymphocytic choriomeningitis virus*  
Advisor: Sean Whelan

**Nabel, Katherine**  
Molecular mechanisms for broad neutralization of emerging RNA viruses  
Advisor: Jonathan Abrham

**Nomburg, Jason**  
*Using Sequencing Approaches to Characterize Tumor Microbial Communities and Viral Transcriptomes*  
Advisors: James DeCaprio and Matthew Meyerson

**Phelps, Meredith**  
*Broadly neutralizing antibody recognition of diverse HIV envelopes modulates effector function*  
Advisor: Alejandro Balazs

**Tartell, Michael**  
*Host Determinants of Viral Entry and Replication*  
Advisor: Sean Whelan

**Welch, Nicole**  
*Harnessing CRISPR-Cas systems for maximally active and multiplexed viral detection*  
Advisor: Pardis Sabeti



 

##  2021 

**Branigan, Timothy**  
*Regulation of cell cycle transitions and CHK1 inhibitor sensitivity by MMB-FOXM1 feedback loops*  
Advisor: James DeCaprio

**Ernandes, Mike**  
*Oxidized Phospholipids as Antivirals and Immune Modulators*  
Advisor: Jonathan Kagan

**Flagg, Meaghan**  
*Mechanisms of disrupted intestinal epithelial homeostasis during HIV infection*  
Advisor: Doug Kwon

**Govande, Apurva**  
Mechanisms of nucleotide signaling in bacterial and metazoan antiviral defense  
Advisor: Philip Kranzusch

**Herrmann, Toby**  
*Molecular mechanisms of rhesus rotavirus entry*  
Advisor: Stephen Harrison

**Karpel, Marshall**  
*Vaccine responses in the context of impaired self-tolerance*  
Advisor: Shiv Pillai

**Mertens, Max**  
*The Relationship Between Herpes Simplex Virus 1 and the Cellular DNA Damage Response*  
Advisor: David Knipe

**Pyle, Jesse**  
*Functional regulation of an arenavirus polymerase complex*  
Advisor: Sean Whelan

**Sangesland, Maya**  
*Germline Encoded B Cell Receptor-Antigen Recognition*  
Advisor: Daniel Lingwood

**Walsh, Michael**  
*Engineering Replication Defective Herpes Simplex Virus 1 Vectors for the Treatment of Cancer*  
Advisor: David Knipe



 

##  2020 

**Cadena, Cristhian**  
*Assembly of RIG-I signaling complexes in antiviral immunity*  
Advisor: Sun Hur

**Chia, Bing Shao**  
*Genome-wide Screen Identifies RTF2 as a Host Restriction Factor that Restricts Influenza A Virus Replication*  
Advisor: Nir Hacohen

**Eaglesham, James**  
*Evolution and Regulation of Antiviral Nucleotide Signaling*  
Advisor: Philip Kranzusch

**Ferreira, Fernanda**  
*New Insights into the Nature of the HIV-2 Reservoir*  
Advisor: Daniel Kuritzkes

**Freije, Catherine**  
*Sequence-informed, Cas13-based technologies for RNA viruses*  
Advisor: Pardis Sabeti

**Joshi, Vinita**  
*Delineating HIV-1 Evolutionary Pathways in an Individual with a Broadly Neutralizing Antibody Response*  
Advisor: Todd Allen

**Lee, Phong**  
*Assembly of Centromeric Nucleosomes in Budding Yeast*  
Advisor: Stephen Harrison

**Lim, Matt**  
*Evaluating measurement error in mass spectrometry-based proteomics*  
Advisor: Steven Gygi

**Lin, Aaron**  
*Characterizing Ebola virus mutation and selection between and within hosts*  
Advisor: Pardis Sabeti

**Liu, Po-Ting**  
*Establishment of the SIV Reservoir and Mechanisms of Viral Rebound in Rhesus Monkeys*  
Advisor: Dan Barouch

**Tomezsko, Phillip**  
*Next-generation sequencing techniques to study HIV-1 transcription and RNA structure*  
Advisor: Daniel Kuritzkes



 

##  2019 

**Barnett, Katherine**  
*Phosphoinositide Regulation of Intracellular Nucleic Acid Sensors*  
Advisor: Jonathan Kagan

**Cabral, Joseph**  
*ATRX Mediated Restriction of Herpes Simplex Virus 1*  
Advisor: David Knipe

**Dudek, Amanda**  
*A Genome-Wide Knock-Out Screen Identifies Novel Host Cell Entry Factor Requirements for Divergent Adeno-Associated Virus Serotypes*  
Advisor: Luk Vandenberghe

**Gootenberg, David**  
*HIV-associated Gut Microbiome Differences and Immune Activation are Dependent on Host Context*  
Advisor: Doug Kwon

**Iampietro, Mark**  
*Immunogenicity and Cross-reactivity of Human and Rhesus Adenoviral Vectors*  
Advisor: Dan Barouch

**Jennewein, Maddy**  
*Harnessing the Fc Region: Antibody Fc Modulation in Infection and Pregnancy*  
Advisor: Galit Alter

**Li, Bo**  
*Genome-wide CRISPR screen Identifies Novel Host Dependency Factors for Influenza A Virus Infection*  
Advisor: Nir Hacohen

**Park, Donglim**  
*Merkel Cell Polyomavirus Oncogenes Generate Targetable Synthetic Lethality*  
Advisor: James DeCaprio

**Schade, Amy**  
*Mechanistic Insights into DREAM and RB Control of the Cell Cycle*  
Advisor: James DeCaprio

**Sharaf, Radwa**  
*Mechanisms of HIV-1 persistence and post-treatment control*  
Advisor: Daniel Kurtizkes

**Tarnita, Roxana**  
*Characterization of the FAM111A-mediated simian virus 40 host range phenotyp*  
Advisor: James DeCaprio

**Wang, Liang Wei**  
*Metabolic Remodeling of Human B-Cells During Latent Epstein-Barr Virus (EBV) Infection*  
Advisor: Benjamin Gewurz

**Wang, May Kwang-Mei**  
*Receptor-targeting small molecule inhibitors of Lassa and Ebola virus entry reveal a critical role for cholesterol in regulating receptor activity*  
Advisor: James Cunningham

**Wang, Xiaoyi**  
*DNA maintainer dependent epigenetic inheritance of gene silencing and histone H3K9 methylation*  
Advisor: Danesh Moazed



 

##  2018 

**Bentley, Peris**  
*The Role of the SMC5/6 Complex in the Papillomavirus Replication Cycle*  
Advisor: Peter Howley

**Blass, Eryn**  
*Innate Immunity and Adenovirus Vector Immunization*  
Advisor: Dan Barouch

**Chiang, Jessica**  
*Activation and Antagonism of RIG-I-Mediated Innate Immune Signaling by Herpes Simplex Virus 1*  
Advisor: Michaela Gack

**Franz, Kate**  
*STING engages distinct antiviral mechanisms to restrict RNA virus and DNA virus replication*  
Advisor: Jonathan Kagan

**Kang, Zi Han**  
*Antibody responses against HIV-1 vaccine candidates*  
Advisor: Dan Barouch

**Lawler, Jessica**  
*Functional analysis of multiple activities associated with the herpes simplex virus-1 DNA polymerase*  
Advisor: Donald Coen

**Neidermyer, William**  
*A Global View of Translation in Vesicular Stomatitis Virus Infected Cells*  
Advisor: Sean Whelan

**Peters, Cole**  
*Restriction of γ34.5-deleted Oncolytic Herpes Simplex Virus-1 in Glioblastoma Stem Cells and Therapies to Treat Them*  
Advisor: Samuel Rabkin

**Timpona, Joseph**  
*VSV vectors as vaccines for emerging viruses and as probes for entry pathways*  
Advisor: Sean Whelan

**Wellman, Tyshia**  
*Epigenetic Alterations Induced by Human Papillomavirus E6 and E7 Oncoproteins*  
Advisor: Karl Münger



 

##  2017 

**Ayeni, Christian**  
*Innate Immune Responses to Replication-Competent and -Deficient HSV-2*  
Advisor: David Knipe

**Dev, Jyoti**  
*Structural and functional characterization of viral membrane proteins by solution NMR spectroscopy*  
Advisor: James Chou

**Harden, Mallory**  
*Dysregulation of Host Cellular microRNA Expression by the Human Papillomavirus E6 and E7 Oncoproteins*  
Advisor: Karl Münger

**Jiang, Sizun**  
*Epstein Barr Virus Drives Cancer through Transcriptional Regulation and Chromatin Dynamics*  
Advisor: Elliott Kieff

**Meyers, Jordan**  
*Cutaneous papillomavirus E6 inhibit NOTCH and TGF-beta signaling to disrupt keratinocyte differentiation*  
Advisor: Karl Münger

**Robinson, Lindsey**  
*Reconstructing the Cell Entry Pathway of an Extinct Virus*  
Advisor: Sean Whelan

**Wilkie, Adrian**  
*The processes mediating capsid trafficking during human cytomegalovirus nuclear egress*  
Advisor: Donald Coen



 

##  2016 

**Berrios, Christian**  
*Simian Virus 40 and Human Polyomavirus Oncogenic Perturbations*  
Advisor: James DeCaprio

**Bricault, Christine**  
*Multivalent Vaccination Strategies with Novel HIV-1 Trimeric Envelope Proteins Elicit Improved Neutralizing Antibody Responses Compared to Monovalent Vaccination Regimens*  
Advisor: Dan Barouch

**Durbin, Ann**  
*Nucleotide modifications of RNA suppress RIG-I antiviral signaling by unique mechanisms*  
Advisor: Lee Gehrke

**Hill, Alison**  
*Emergence of simian immunodeficiency virus in rhesus macaques is characterized by changes in structural and accessory genes that enhance fitness in the new host species*  
Advisor: Welkin Johnson

**Ita, Sergio**  
*Adaptive Evolution of the SIV Envelope Protein during Early SIV Infection*  
Advisor: Welkin Johnson

**Provine, Nicholas Mcdermott**  
*CD4 T Cells Regulate Adenovirus Vector-Elicited Cellular and Humoral Immune Responses*  
Advisor: Dan Barouch

**Rahmberg, Andrew**  
*Gene Expression and CD4+ T Cell Susceptibility to SIV*  
Advisor: Paul Johnson



 

##  2015 

**Conwell, Sara**  
*TRIM27 in HSV-1 Infection: A Story of Loss and Death*  
Advisor: David Knipe

**Davis, Meredith**  
*Evasion of MDA5-mediated Innate Immunity by Paramyxoviruses*  
Advisor: Michaela Gack

**Herrman, Marissa Ann**  
*Neutralizing Antibodies to Epstein Barr Virus in the Rhesus Macaque Animal Model and in Humans*  
Advisor: Frederick Wang

**Jurado, Kellie Ann**  
*Allosteric integrase inhibitors reveal a role for integrase during HIV-1 maturation*  
Advisor: Alan Engelman

**Lee, Jennifer**  
*Epigenetic Regulation of Lytic and Latent Herpes Simplex Virus 1 Infection*  
Advisor: David Knipe

**Leigh, Kendra**  
*Structural Studies of a Subunit of the Murine Cytomegalovirus Nuclear Egress Complex*  
Advisor: James Hogle

**Piccinotti, Silvia**  
*Rabies Glycoprotein-Mediated Uptake into Epithelial Cells and Compartmentalized Primary Neuronal Culture*  
Advisor: Sean Whelan

**Soghoian, Damien**  
*HIV-specific CD4 T cells and Viral Control*  
Advisor: Bruce Walker

**Soh, Timothy**  
*Single particle studies of vesicular stomatitis virus assembly*  
Advisor: Sean Whelan

**Sun, Eileen**  
*Investigating host protein function and developing assays for influenza virus infection*  
Advisor: Xiaowei Zhuang

**Thorpe, Lauren**  
*PI3K regulatory subunit p85alpha plays a tumor suppressive role in the transformation of mammary epithelial cells*  
Advisor: Jean Zhao

**Yoon, Rosa**  
*Merkel Cell Polyomavirus Small T Antigen Perturbs the Cellular DNA Damage Response*  
Advisor: James DeCaprio



 

##  2014 

**Ellis, Laura**  
*Investigating the roles of the JC virus agnogene and regulatory region using a naturally occurring, pathogenic viral isolate*  
Advisor: Igor Koralnik

**Gardner, Matthew**  
*TARGETING THE CD4- AND CORECEPTOR-BINDING SITES OF THE HIV-1 ENVELOPE GLYCOPROTEIN*  
Advisor: Michael Farzan

**Guth, Charles**  
*Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus (HIV-1) Capsid*  
Advisor: Joseph Sodroski

**Mahan, Alison**  
*Regulation and Programming of Antibody Effector Function through IgG Glycosylation*  
Advisor: Galit Alter

**Matreyek, Kenneth**  
*HIV-1 capsid engages nucleoporin NUP153 to promote viral nuclear entry*  
Advisor: Alan Engelman

**McCarthy, Kevin**  
*Viral and Host Determinants of Primate Lentivirus Restriction by Old World Primate TRIM5alpha Proteins*  
Advisor: Welkin Johnson

**Oztop, Ilker**  
*THE FUNCTIONAL INTERPLAY BETWEEN TNPO3, CPSF6 AND HIV-1 CA*  
Advisor: Alan Engelman

**Quinlan, Brian**  
*Directed Evolution of Peptide Inhibitors of HIV-1 Entry*  
Advisor: Michael Farzan

**Schafer, Jamie**  
*Rhesus macaque KIR recognition of MHC class I molecules: Ligand identification and modulation of interaction by SIV peptides*  
Advisor: David Evans

**Teigler, Jeffrey**  
*Differential Innate Immune Stimulation Elicited by Adenovirus and Poxvirus Vaccine Vectors*  
Advisor: Dan Barouch

**Tong, Haoxuan**  
*PI3K Isoform Dependence and Translational Regulation of c-MYC in PTEN-Deficient Leukemia*  
Advisor: Thomas Roberts



 

##  2013 

**Bollman, Brooke**  
*Role of the Capsid Helix 4-5 Loop in Equine Infectious Anemia Virus Infection*  
Advisor: Joseph Sodroski  
  
**Clark, Margaret**  
*Exploring Dengue Virus Entry Through Small Molecule Inhibition and Mutagenesis of the Envelope Protein*  
Advisor: Priscilla Yang

**Lim, Hui Jun**  
*Dynamic regulation of histone lysine methylation via the ubiquitin-proteasome system.*  
Advisor: Yang Shi

**Orzalli, Megan**  
*Inhibition of Nuclear DNA Sensing by Herpes Simplex Virus 1*  
Advisor: David Knipe

**Tan, Meng Kwang Marcus**  
*Deciphering the biological functions of F-box proteins through the use of Parallel Adaptor Capture (PAC) proteomics.*  
Advisor: J.Wade Harper

**Tan, Min Jie Alvin**  
*Identification of the Cellular Proteins and Pathways Engaged by the Bovine Papillomavirus Type 1 E6 and E7 Proteins*  
Advisor: Peter Howley

**Yen, Po-Jen**  
*SIV envelope glycoprotein determinants of macrophage tropism and their relationship to neutralization sensitivity and CD4-independent cell-to-cell transmission*  
Advisor: Dana Gabuzda



 

##  2012 

**Alpert, Michael**  
*Antibodies in Vaccine Protection against SIV and HIV-1 Infection*  
Advisor: David Evans

**Bruchez, Anna**  
*Niemann-Pick C1 is essential for Ebola virus infection and a target of small molecule inhibitors*  
Advisor: James Cunningham

**DeGrace, Marciela**  
*RNAi screens in primary human lung cells reveal Hermansky-Pudlak Syndrome proteins as influenza suppressors*  
Advisor: Nir Hacohen

**Kim, Irene**  
*Mechanisms of membrane disruption by viral entry proteins*  
Advisor: Stephen Harrison

**Kranzusch, Philip**  
*Architecture and regulation of the arenavirus polymerase complex*  
Advisor: Sean Whelan

**Lee, Amy**  
*Ribosome-mediated specificity in vesicular stomatitis virus mRNA translation defines a new role for rpL40 during initiation*  
Advisor: Sean Whelan

**Mefford, Megan**  
*MOLECULAR AND BIOINFORMATIC ANALYSIS OF NEUROTROPIC HIV ENVELOPE GLYCOPROTEINS*  
Advisor: Dana Gabuzda

**Mukerji, Joya**  
*A NOVEL EXOCYST-BASED MECHANISM FOR HIV NEF-MEDIATED ENHANCEMENT OF INTERCELLULAR NANOTUBE FORMATION*  
Advisor: Dana Gabuzda

**Rahman, Shaila**  
*Molecular insight into function of the evolutionarily conserved Brd4 extraterminal domain (ET) and mechanism of Brd4 functions in human diseases*  
Advisor: Peter Howley

**Spangle, Jennifer**  
*Regulation of Growth Factor and Nutrient Sensing Pathways by Human Papillomavirus E6 Proteins*  
Advisor: Karl Münger



 

##  2011 

**De Leon-Vazquez, Erika**  
*Investigation of the Roles of the KSHV Latency Associated Nuclear Antigen Internal Regions in Episome Persistence.*  
Advisor: Kenneth Kaye

**Morelli, Marco**  
*The Role of HIV-1 Membrane in Neutralization by gp41 MPER-directed Broadly Neutralizing Antibodies*  
Advisor: Stephen Harrison  
  
**Schmidt, Aaron**  
*Inhibition by Small Molecules and Peptides of Dengue-virus Fusion and Entry*  
Advisor: Stephen Harrison



 

##  2010 

**Aoki, Scott**  
*The Role of Outer Capsid Glycoprotein VP7 in Assembly, Neutralization, and Maturation of the Rotavirus Triple Layered Particle*  
Advisor: Stephen Harrison  
  
**Rogers, Thomas**  
*Intrinsic Immune Response to Viral Replication in Primates*  
Advisor: Norman Letvin

**Uzri, Dina**  
*RIG-I-Dependent Innate Immune Signaling by Hepatitis C Virus RNAS*  
Advisor: Lee Gehrke



 

##  2009 

**Erlandson, Karl**  
*Interactions of the SecY Channel and the SecA ATPase with a Translocating Polypeptide*  
Advisor: Tom Rapoport

**Johnson, Karen**  
*THE INHIBITION OF TYPE I INTERFERON SIGNALING BY HERPES SIMPLEX VIRUS 1*  
Advisor: David Knipe

**Laird, Melissa**  
*HIV/SIV VARIABLE LOOPS AS TARGETS AND ELICITORS OF ANTIBODIES THAT NEUTRALIZE VIRAL INFECTIVITY*  
Advisor: Ronald Desrosiers

**Maliszewski, Laura**  
*The Role of miRNAs in HIV Infection of Primary Macrophages*  
Advisor: Judy Lieberman

**Rud, Debrah**  
*Identification of FAM111A as a Novel Simian Virus 40 Large T Antigen Binding Protein that Affects Viral Host Range*  
Advisor: James DeCaprio

**Silva, Laurie**  
*The Roles of Phosphorylation and the Carboxy-terminus in the Function of the Human Cytomegalovirus Processivity Factor, UL44*  
Advisor: Donald Coen



 

##  2008 

**Boutwell, Christian**  
*INVESTIGATION OF THE ADAPTATION OF HIV-1C TO THE HOST CTL IMMUNE RESPONSE*  
Advisor: Myron Essex

**Bowman, John**  
*Characterization of Expression of the Herpes Simplex Virus Type-1 ICP22 and Us1.5 Proteins*  
Advisor: Priscilla Schaffer

**Cureton, David**  
*VIRAL AND CELLULAR DETERMINANTS OF VESICULAR STOMATITIS VIRUS ENTRY*  
Advisor: Sean Whelan

**Fontaine Rider, Errin**  
*HERPES SIMPLEX VIRUS IMMEDIATE EARLY PROTEINS AND EFFECTS ON TRANSLATION*  
Advisor: David Knipe

**Garcia, Maria**  
*The molecular basis of Herpesvirus Saimiri oncogenicity*  
Advisor: Jae Jung

**Huang, I-Chueh**  
*ENZYMATIC REGULATION OF VIRAL ENTRY*  
Advisor: Michael Farzan

**Ivanovic, Tijana**  
*From Virion to Viral Factory: Reovirus Particle Transformations Leading to Cell Entry and Productive Infection*  
Advisor: Max Nibert

**Kushnir, Anna**  
*THE EFFECT OF CELLULAR STRESS-INDUCED FACTORS ON HSV-1 GENE EXPRESSION AND REPLICATION*  
Advisor: Priscilla Schaffer

**Manuel, Edwin**  
*Immunodominance in Primate Immunodeficiency Virus Infection*  
Advisor: Norman Letvin

**Mirchandani, Kanchan**  
*A role for the Fanconi Anemia pathway in error-prone DNA damage tolerance*  
Advisor: Alan D'Andrea

**Nguyen, Christine**  
*CENTROSOMAL AND MITOTIC ABERRATIONS: MECHANISTIC INSIGHTS INTO HPV16 E7 ONCOPROTEIN-INDUCED GENOMIC DESTABILIZATION*  
Advisor: Karl Münger

**Radoshitzky, Sheli**  
*CELL ENTRY OF NEW WORLD HEMORRHAGIC FEVER ARENAVIRUSES*  
Advisor: Michael Farzan

**Trask, Shane**  
*The mechanism of membrane penetration by rotavirus*  
Advisor: Stephen Harrison

**Wass, Amanda**  
*BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE VPg URIDYLYLATION COMPLEX OF POLIOVIRUS*  
Advisor: James Hogle

**Wu, Su**  
*YY1 functions in homologous recombination DNA repair and mice spermatogenesis*  
Advisor: Yang Shi



 

##  2007 

**Arnold, Michelle**  
*Roles of muNS in Reovirus Factory Formation*  
Advisor: Max Nibert

**Bryant, Kevin**  
*REGULATION OF TRANSLATION DURING HERPES SIMPLEX VIRUS-1 INFECTION*  
Advisor: Donald Coen

**Chen, Adrienne**  
*Epstein-Barr Virus Nuclear Antigen 3B- and 3C-regulated cellular genes in virus-immortalized B cells*  
Advisor: Frederick Wang

**Dunfee, Rebecca**  
*ENVELOPE-RECEPTOR INTERACTIONS OF NEUROTROPIC HIV*  
Advisor: Dana Gabuzda

**He, Xi**  
*Regulation of SNF2h Chromatin Remodeling Activity*  
Advisor: Robert Kingston  
  
**Kattenhorn, Lisa**  
*Identification and Characterization of a Novel Deubiquitinating Activity Conserved Within the Herpesvirus Large Tegument Proteins*  
Advisor: Hidde Ploegh

**Link, Malen**  
*MECHANISM OF EXPRESSION AND FUNCTIONAL ANALYSIS OF HERPES SIMPLEX VIRUS TYPE-1 PROTEINS OBPC-1 AND OBPC-2*  
Advisor: Priscilla Schaffer

**Perron, Michel**  
*TRIM5ahu: An Innate Cellular Defense Against N-tropic Murine Leukemia Virus Infection in Humans*  
Advisor: Joseph Sodroski

**Redd, Andrew**  
*Human Immunodeficiency Virus Type 1 Subtype C and Hematopoiesis*  
Advisor: Myron Essex

**Yoder, Joshua**  
*Molecular Rearrangements of Recombinant and Authentic Rotavirus VP5\**  
Advisor: Phil Dormitzer



 

##  2006 

**Agopian, Kristin**  
*Characterization of Primary HIV-1 NEF Alleles and Their Association with P21-Activated Kinase 2*  
Advisor: Dana Gabuzda

**Gomila, Raúl**  
*Identification and Characterization of Host Factors that Bind the Conserved 3' Terminal Stem Loop RNA of Flaviviruses*  
Advisor: Lee Gehrke

**Greenland, John**  
*Vaccine antigen expression and immune responses*  
Advisor: Norman Letvin

**Hughes, Christina**  
*Menin is a Component of SET1-Like Histone Methyltransferase Complexes that Regulate Gene Expression*  
Advisor: Matthew Meyerson

**Kelley-Clarke, Brenna**  
*Characterization and functional assessment of the Kaposi's sarcoma herpesvirus latency-associated nuclear antigen C-terminal chromosome binding domain*  
Advisor: Kenneth Kaye  
  
**Melroe, Gregory**  
*Herpes Simplex Virus Inhibition of Innate Type-I Interferon Induction*  
Advisor: David Knipe  
  
**Myers, Kimberly**  
*Membrane Perforation and Related Structural Transitions by Reovirus Particles*  
Advisor: Max Nibert  
  
**Skaar, Jeffrey**  
*Biochemical and Genetic Characterization of Cullin 7- and PARC-containing Complexes*  
Advisor: James DeCaprio



 

##  2005 

**Barbera, Andrew**  
*Role of the Latency Associated Nuclear Antigen N-terminus in Chromosome Association and Kaposi's Sarcoma-Associated Herpesvirus DNA Persistence*  
Advisor: Kenneth Kaye

**Chan, Amanda**  
*The Role of Intramolecular Interactions in HHR23A Function in Ubiquitin-Mediated Protein Degradation*  
Advisor: Peter Howley

**Jackson, Shawn**  
*Vaccine-Elicited Memory Cytotoxic T Lymphocytes*  
Advisor: Norman Letvin

**Kasper, Jocelyn**  
*SV40 Large T Antigen Inactivates CUL7, a p53-Interacting Cullin*  
Advisor: James DeCaprio

**Lu, Richard**  
*Genetic Analyses of Human Immunodeficency Virus Type 1 Integrase Mutants*  
Advisor: Alan Engelman

**Petrillo, Jessica**  
*Characterization of RNA and Protein Determinants of Alfalfa Mosaic Virus Replication*  
Advisor: Lee Gehrke

**Poulin- Porter, Danielle**  
*The Carboxyl-Terminal Domain of Large T Antigen is Essential for the Simian Virus 40 Life Cycle*  
Advisor: James DeCaprio

**Suscovich, Todd**  
*Modulation of Tapasin Expression in Primary Effusion Lymphoma*  
Advisor: David Scadden

**Thomas, Seddon**  
*The Role of Chemokine Receptors in CD1D-Restricted NK T Cell Trafficking*  
Advisor: Andrew Luster

**Wong, Sharyl**  
*Prediction and Characterization of Genetic Interactions*  
Advisor: Frederick Roth



 

##  2004 

**Appleton, Brent**  
*The Three-Dimensional Structure and Functional Studies of the Human Cytomegalovirus DNA Polymerase Subunit, UL44*  
Advisor: James Hogle

**Hershberger, Karen**  
*Diverse Killer-cell Ig-like Receptors (KIRs) of Rhesus and Sabaeus Monkeys: Evidence for Recombination Events in the Evolution of KIRs*  
Advisor: Norman Letvin  
  
**Holm, Geoffrey**  
*Mechanisms of Bystander T Cell Apoptosis in HIV-1 Infection*  
Advisor: Dana Gabuzda  
  
**Lorenzo, Mayra**  
*Downregulation of MHC Class I Molecules by Herpesviruses: Usurpation of Intracellular Trafficking Pathways*  
Advisor: Hidde Ploegh

**Mehle, Andrew**  
*HIV-1 VIF: A Novel SOCS-Box Protein that Targets APOBEC3G for Proteasomal Degradation*  
Advisor: Dana Gabuzda

**Peyerl, Friedrich**  
*Structural Constraints on Primate Immunodeficiencey Virus Escape from Cytotoxic T Lymphocytes*  
Advisor: Norman Letvin

**Smith, Jason**  
*Thiol-dependent Activation of Alpharetrovirus Infection*  
Advisor: James Cunningham



 

##  2003 

**Day, Cheryl**  
*CD4+ T-Helper Cell Responses in Hepatitis C Virus Infection*  
Advisor: Bruce Walker

**Klucking, Sara**  
*Cytopathic Avian Retroviruses and the Death Receptor TVB*  
Advisor: John Young

**LaBonte, Jason**  
*HIV-1 Single Round Vector Systems for the Expression of Envelope Glycoproteins in Primary Cells*  
Advisor: Joseph Sodroski

**Lin, Jeffrey**  
*Epstein-Barr Virus Nuclear Antigen 3C (EBNA3C) Regulates Transcription through Viral and Cellular Factors*  
Advisor: Elliott Kieff

**Luftig, Micah**  
*Characterization of Epstein-Barr Virus Latent Membrane Protein 1 Mediated NFkB Activation*  
Advisor: Elliott Kieff

**Randell, John**  
*Processivity of the Herpes Simplex Virus DNA Polymerase: Role of High-Affinity DNA Binding by the Processivity Subunit*  
Advisor: Donald Coen

**Wensel, David**  
*A Virus-Virus Interaction Circumvents the Virus Receptor Requirement for Infection by Pathogenic Retroviruses*  
Advisor: James Cunningham



 

##  2002 

**Cooper, Andrew**  
*Epstein-Barr Virus Nuclear Antigen 3A (EBNA-3A) Can Inhibit c-myc Expression and Lymphoblastoid Cell Growth*  
Advisor: Elliott Kieff

**LaBonte, Michelle**  
*Characterization of the CD94/NKG2 Family of Molecules in the Rhesus Monkey*  
Advisor: Norman Letvin

**McNamee, Elizabeth**  
*Regulation of HSV Gene Expression: Two Viral Functions Implicated in the Stimulation of Late Gene Transcription*  
Advisor: David Knipe

**Taylor, Travis**  
*Intranuclear Localization of the Herpes Simplex Virus ICP8 Protein*  
Advisor: David Knipe



 

##  2001 

**Brockman, Mark**  
*Mechanisms of the Humoral Immune Response to Herpes Simplex Virus Infection*  
Advisor: David Knipe

**Furman, Craig**  
*DEF-1: An ARF Gap that Localizes to Focal Adhesions and Regulates Cell Attachment and Motility*  
Advisor: Thomas Roberts

**Kleijnen, Mauritius**  
*Ubiquitin-like hPLIC Proteins: A Link between Ubiquitination and Proteasomal Degradation*  
Advisor: Peter Howley

**Kolchinsky, Peter**  
*CD4-Independence of a CCR5-Using HIV-1 Primary Isolate*  
Advisor: Joseph Sodroski

**Mittler, Ellis Stewart**  
*Mechanisms and Pathways of Picornaviral Entry into HeLa Cells*  
Advisor: James Hogle



 

##  2000 

**Adkins- Huet, Heather**  
*Indentification and Characterization of TNFR-like Receptors for Subgroups B, D and E Avian Leukosis Viruses: Two Isoforms of a Common Receptor Explain Non-reciprocal Receptor Interference between Cytopathic and Non-cytopathic Avian Retroviruses*  
Advisor: John Young

**Csejtey Olland, Andrea**  
*Structure of the Reovirus Outer Capsid Protein Sigma 3*  
Advisor: Stephen Harrison

**DeTulleo, Louis**  
*Viral Usage of the Clathrin Endocytic Pathway*  
Advisor: Tomas Kirchhausen

**Jun, Helen (Toni)**  
*Analysis of Cellular Signaling Pathways Activated by Polyomavirus Middle T Antigen*  
Advisor: Thomas Roberts

**Snitkovsky, Sophie**  
*Targeting of Retroviral Vectors to Specific Cell Types Mediated by Soluble Retroviral Receptor-Ligand Bridge Proteins*  
Advisor: John Young



 

##  1999 

**Means, Robert**  
*Factors Affecting the Antigenicity and Immunogenicity of SIVmac Envelope*  
Advisor: Ronald Desrosier

**Powell, Christina M. H.**  
*Role of the Mammalian Transcription Factor LSF at the G1/S Transition of the Cell Cycle*  
Advisor: Ulla Hansen

**Rizzuto, Carlo**  
*Molecular Interactions in HIV-1 Entry*  
Advisor: Joseph Sodroski



 

##  1998 

**Lu, Wange**  
*Pak1 Kinase: A Nck Adaptor Interacting Protein*  
Advisor: Bruce Mayer

**Puder, Mark**  
*Intracellular Movement and Binding of Leukotriene C4 and Glutathione Conjugates*  
Advisor:



 

##  1997 

**Borras-Rodriquez, Ana María**  
*Analysis of the Promoter Elements in the Epstein-Barr Virus Lytic Switch Gene, BZLF1*  
Advisor: Jack Strominger

**Chow, Connie Shui-Yi**  
*Structure/Function Analysis of the Herpes Simplex Virus DNA Polymerase Subunit UL42: A Novel Processivity Factor*  
Advisor: Donald Coen

**Peng, Cheng-Yuan**  
*Regulation of Human Cdc25C Phosphatase*  
Advisor: Helen Piwnica-Worms

**Stubdal, Hilde**  
*Novel Mechanism for Inactivation of the pRB-related Proteins p130 and p107 Mediated by the J-domain of SV40 large T Antigen*  
Advisor: James DeCaprio

**Uprichard, Susan L.**  
*Expression and Assembly of the HSV DNA Replication Proteins*  
Advisor: David Knipe



 

##  1996 

**Puglielli, Maryann Theresa**  
*Regulation of EBNA Gene Promoters in Epstein-Barr Virus Immortalized B Cells*  
Advisor:



 

##  1995 

**Bachelder, Robin**  
*Characterization of the CD4-Specific Antibody Response of a Recombinant Soluble CD4-Immunized, HIV-1-Infected Human through the Construction of a Combinatorial Fab Library*  
Advisor: Norman Letvin

**Baradaran, Khandan**  
*Identification and Characterization of a Novel HSV-1 Origin Binding Protein*  
Advisor: Priscilla Schaffer

**Curtin, Kathryn**  
*Regulated Nuclear Entry of the period Protein Contributes to a Circadian Clock in Drosophila*  
Advisor:

**Freeman, Robert**  
*Molecular Cloning and Characterization of the SH2 Domain-containing Protein Tyrosine Phosphatase SH-PTP2*  
Advisor: Benjamin Neel

**Hooper, Jay**  
*Analysis of the Mechanism of Reovirus Entry into Cells*  
Advisor: Bernie Fields

**Kramer, Martha**  
*Quantification of Herpes Simplex Virus DNA and Transcripts during Latent Infection in Mouse Trigeminal Ganglia by Reverse Transcriptase PCR*  
Advisor: Donald Coen

**Lee, Jeng-Shin**  
*Transcriptional Regulation by Yin-Yang 1 and Adenovirus E1A*  
Advisor: Yang Shi

**Li, John**  
*Construction and Characterization of Recombinant Simian/Human Immunodeficiency Virus (SHIV) Expressing the HIV-1 Envelope Glycoproteins*  
Advisor: Joseph Sodroski

**Renjifo, Boris**  
*Human T-cell Leukemia Virus Type I (HTLV-I): Pathogenesis of Tropical Spastic Paraparesis/HTLV-I-associated Myelopathy (TSP/HAM)*  
Advisor: Myron Essex



 

##  1994 

**Agarwal, Sadhana**  
*Regulation of Post-Translational Modifications of c-fos and c-jun*  
Advisor: Thomas Roberts

**Edmonson, Paul**  
*Development of a Simian Immunodeficiency Virus (SIV) Pathogen*  
Advisor:

**Shirodkar, Suman**  
*Functional Interactions of the Transcription Factor E2F with Cellular Proteins*  
Advisor: David Livingston



 

##  1993 

**Bartel, David**  
*RNA Recognition and Catalysis: I. The HIV Rev-RRE Interaction II. New Ribozymes from Random Sequences*  
Advisor: Jack Szostak

**Casaz, Paul**  
*Regulation of Transcription by Simian Virus 40 Large Tumor Antigen*  
Advisor: Ulla Hansen

**Morin, Merribeth**  
*Pathogenesis of Reovirus Infection in the Lungs*  
Advisor: Bernie Fields

**Prentice, Holly**  
*Characteriztion of Heat Shock Factor and Mammalian Promoter Elements in the Fission Yeast Schizosaccharomyces pombe*  
Advisor: Robert Kingston

**Xia, Kai**  
*Phosphorylation of the HSV-1 Major Regulatory Protein ICP4*  
Advisor: David Knipe



 

##  1992 

**Burns (Wooley), Dawn**  
*Envelope Sequence Variation and Immune Selection of Simian Immunodeficiency Virus (SIV) in Persistently Infected Rhesus Monkeys*  
Advisor: Ronald Desrosiers

**Farnet, Chris**  
*The Integration and Circularization of Human Immunodeficiency Virus Type 1 DNA in vitro*  
Advisor:

**Jacobson, Jennie**  
*Individual and Combinatorial Effects of Non-Lethal Mutations on HSV-1 Pathogenesis and Reactivatable Latent Infection in a Mouse Model*  
Advisor: Donald Coen

**Mundschau Kasman, Laura**  
*Identification of Platelet-Derived Growth Factor Signal Transduction Second Messenger Pathways*  
Advisor: Douglas Faller



 

##  1991 

**Batson, Susan**  
*In Vitro Transcriptional Analysis of in Vivo Assembled Chromatin*  
Advisor: Ulla Hansen

**Kristal, Bruce**  
*Multiple Roles of the Feline Leukemia Virus Envelope Glycoprotein*  
Advisor:

**Mullen, Mary**  
*Alternative Pre-mRNA Splicing of a-Tropomyosin*  
Advisor:

**Shepard, Alyssa**  
*Genetic Analysis of the Herpes Simplex Virus Type 1 Regulatory Protein ICP4*  
Advisor: Neal DeLuca

**Young, Alexander**  
*Polyoma Virus Middle T Effects on Elements of Signal Transduction*  
Advisor: Thomas Benjamin



 

##  1988 

**Smith, Colton**  
*Molecular Genetics of the Herpes Simplex Virus Type 2 Gene Encoding ICP4*  
Advisor: Priscilla Schaffer